APOE mouse monoclonal antibody, clone OTI3F1 (formerly 3F1)
Applications & Recommended Dilution
Applications & DilutionRecommended Dilution- Reactivity
- Human
- Assay
- IHC
- Reactivity
- Human
- Assay
- WB
Product Images
Product ImagesImages
Product Specifications
SpecificationsProduct Specifications- Species Reactivity
- Human
- Applications
- IHCWB
- Clone name
- OTI3F1
- Calculated molecular weight
- 34.2 kDa
- Immunogen
- Full length human recombinant protein of human APOE (NP_000032) produced in HEK293T cell.
- Isotype
- IgG2b
- Host species
- Mouse
- Clonality
- Monoclonal
- Purification method
- Affinity Purification
- Uniprot-A
- P02649
- WB
- 1:2000
- IHC
- 1:150
- Shipping
- They are shipped out with dry ice/blue ice unless customers require otherwise
- Storage Condition
- Store at -20°C PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.Stable for 12 months from date of receipt.
- Formulation
- Liquid
- Storage Buffer
- PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq, Jul 2008]
Storage & Shipping
Storage & ShippingHandling01Shipping
They are shipped out with dry ice/blue ice unless customers require otherwise
02Storage Condition
Store at -20°C PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.Stable for 12 months from date of receipt.
03Formulation
Liquid
04Storage Buffer
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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