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Mouse Monoclonal AntibodiesCat. No. GAM918721

RNF20 mouse monoclonal antibody,clone OTI2B9

AliasesRNF20
ReactivityHuman / Mouse / Rat
ApplicationsIHC · WB
Host / ClonalityMouse / Monoclonal
Lead timeIn stock · ships in 48h
$169/ 50μlIn stock 199 · Ready to ship
50μl$169
100μl$299

Applications & Recommended Dilution

Applications & DilutionRecommended Dilution
IHC
Recommended dilution1:150
Reactivity
Human / Mouse / Rat
Assay
IHC
WB
Recommended dilution1:500
Reactivity
Human / Mouse / Rat
Assay
WB

Product Images

Product ImagesImages

Product Specifications

SpecificationsProduct Specifications
Core Attributes CORE ATTRIBUTES
Species Reactivity
HumanMouseRat
Applications
IHCWB
Clone name
OTI2B9
Calculated molecular weight
113.5 kDa
Immunogen
Human recombinant protein fragment corresponding to amino acids 493-754 of human RNF20 (NP_062538) produced in E.coli.
Isotype
IgG2b
Host species
Mouse
Clonality
Monoclonal
Purification method
Affinity Purification
Uniprot-A
Q5VTR2
Recommended Dilution RECOMMENDED DILUTION
WB
1:500
IHC
1:150
Product Properties PRODUCT PROPERTIES
Shipping
They are shipped out with dry ice/blue ice unless customers require otherwise
Storage Condition
Store at -20°C PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.Stable for 12 months from date of receipt.
Formulation
Liquid
Storage Buffer
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

The protein encoded by this gene shares similarity with BRE1 of S. cerevisiae. The protein encoded by this human gene is an E3 ubiquitin ligase that regulates chromosome structure by monoubiquitinating histone H2B. This protein acts as a putative tumor suppressor and positively regulates the p53 tumor suppressor as well as numerous histone H2A and H2B genes. In contrast, this protein also suppresses the expression of several protooncogenes and growth-related genes, including many genes that are induced by epidermal growth factor. This gene selectively suppresses the expression of some genes by interfering with chromatin recruitment of transcription elongation factor SII (TFIIS). [provided by RefSeq, Feb 2012]

Storage & Shipping

Storage & ShippingHandling

01Shipping

They are shipped out with dry ice/blue ice unless customers require otherwise

02Storage Condition

Store at -20°C PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.Stable for 12 months from date of receipt.

03Formulation

Liquid

04Storage Buffer

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

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