CD137L mouse monoclonal antibody,clone OTI4G5

Name: CD137L mouse monoclonal antibody,clone OTI4G5
SKU: GAM924325
Price: 169 CNY
Availability: InStock

AliasesTNFSF9

ReactivityHuman

ApplicationsFC

Host / ClonalityMouse / Monoclonal

Lead timeIn stock · ships in 48h

$169/ 50μlIn stock 199 · Ready to ship

50μl$169

100μl$299

Applications & Recommended Dilution

Applications & DilutionRecommended Dilution

Recommended dilutionNo data

Reactivity: Human
Assay: FC

Product Images

Product ImagesImages

CD137L mouse monoclonal antibody,clone OTI4G5 图 1 — Image 1 / 2Flow cytometric analysis of living 293T cells transfected with CD137L overexpression plasmid, Red)/empty vector (Blue) using anti-CD137L antibody (GAM924325). Cells incubated with a non-specific antibody (Green) were used as isotype control (1:100).

CD137L mouse monoclonal antibody,clone OTI4G5 图 2 — Image 2 / 2Flow cytometric analysis of living Raji cells, using anti-CD137L antibody (GAM924325, Red), compared to an isotype control (green), and a PBS control (blue) (1:100).

Product Specifications

SpecificationsProduct Specifications

Core Attributes CORE ATTRIBUTES

Species Reactivity: Human

Applications: FC

Clone name: OTI4G5

Calculated molecular weight: 26.4 kDa

Immunogen: Full length human recombinant protein of human CD137L (NP_003802) produced in HEK293T cell.

Isotype: IgG2b

Host species: Mouse

Clonality: Monoclonal

Purification method: Affinity Purification

Uniprot-A: P41273

Product Properties PRODUCT PROPERTIES

Shipping: They are shipped out with dry ice/blue ice unless customers require otherwise

Storage Condition: Store at -20°C PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.Stable for 12 months from date of receipt.

Formulation: Liquid

Storage Buffer: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9/4-1BB, which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9/4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. The ligand encoded by this gene, TNFSF9/4-1BBL, has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine has also been shown to be required for the optimal CD8 responses in CD8 T cells. This cytokine is expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interaction. [provided by RefSeq, Oct 2008]