FCGR3A mouse monoclonal antibody, clone OTI12D8

Name: FCGR3A mouse monoclonal antibody, clone OTI12D8
SKU: GAM924744
Price: 169 CNY
Availability: InStock

AliasesCD16

ReactivityHuman

ApplicationsFC · WB

Host / ClonalityMouse / Monoclonal

Lead timeIn stock · ships in 48h

$169/ 50μlIn stock 199 · Ready to ship

50μl$169

100μl$299

Applications & Recommended Dilution

Applications & DilutionRecommended Dilution

Recommended dilutionNo data

Reactivity: Human
Assay: FC

Recommended dilution1:1000

Reactivity: Human
Assay: WB

Product Images

Product ImagesImages

FCGR3A mouse monoclonal antibody, clone OTI12D8 图 1 — Image 1 / 2Flow cytometric analysis of living 293T cells transfected with FCGR3A overexpression plasmid, Red)/empty vector (Blue) using anti-FCGR3A antibody (GAM924744). Cells incubated with a non-specific antibody (Green) were used as isotype control.（1：100）

FCGR3A mouse monoclonal antibody, clone OTI12D8 图 2 — Image 2 / 2HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY FCGR3A (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-FCGR3A antibody (Cat# GAM924744)(1:1000)

Product Specifications

SpecificationsProduct Specifications

Core Attributes CORE ATTRIBUTES

Species Reactivity: Human

Applications: FCWB

Clone name: OTI12D8

Calculated molecular weight: 29.09 kDa

Immunogen: Full length human recombinant protein of human FCGR3A (NP_001121065) produced in HEK293T cell.

Isotype: IgG1

Host species: Mouse

Clonality: Monoclonal

Purification method: Affinity Purification

Uniprot-A: P08637

Recommended Dilution RECOMMENDED DILUTION

WB: 1:1000

Product Properties PRODUCT PROPERTIES

Shipping: They are shipped out with dry ice/blue ice unless customers require otherwise

Storage Condition: Store at -20°C PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.Stable for 12 months from date of receipt.

Formulation: Liquid

Storage Buffer: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].