Products

Custom Services

Technical Support

News Center

Promotions

About Us

Products

Custom Services

Technical Support

News Center

Promotions

About Us

Mouse Monoclonal AntibodiesCat. No. GAM611869

Anti-BIRC7 (Livin) mouse monoclonal antibody, clone OTI1D12 (formerly 1D12)

Name: Anti-BIRC7 (Livin) mouse monoclonal antibody, clone OTI1D12 (formerly 1D12)
SKU: GAM611869
Price: 169 CNY
Availability: InStock

AliasesBIRC7

ReactivityHuman

ApplicationsFC · IHC · WB

Host / ClonalityMouse / Monoclonal

Lead timeIn stock · ships in 48h

$169/ 50μlIn stock 200 · Ready to ship

50μl$169

100μl$299

Applications & Recommended Dilution

Applications & DilutionRecommended Dilution

Recommended dilutionNo data

Reactivity: Human
Assay: FC

IHC

Recommended dilution1:50

Reactivity: Human
Assay: IHC

Recommended dilution1:1000

Reactivity: Human
Assay: WB

Product Images

Product ImagesImages

Anti-BIRC7 (Livin) mouse monoclonal antibody, clone OTI1D12 (formerly 1D12) 图 1 — Image 1 / 6No text caption for this image

Anti-BIRC7 (Livin) mouse monoclonal antibody, clone OTI1D12 (formerly 1D12) 图 2 — Image 2 / 6Flow cytometric analysis of Hela cells, using anti-BIRC7 antibody (GAM611869), (Red) compared to a nonspecific negative control antibody (Blue).

Anti-BIRC7 (Livin) mouse monoclonal antibody, clone OTI1D12 (formerly 1D12) 图 3 — Image 3 / 6Western blot analysis of extracts (10ug) from 10 Human tissue by using anti-BIRC7 monoclonal antibody at 1:200 (1: Testis; 2: Omentum; 3: Uterus; 4: Breast; 5: Brain; 6: Liver; 7: Ovary; 8: Thyroid gland; 9: colon;10: spleen).

Anti-BIRC7 (Livin) mouse monoclonal antibody, clone OTI1D12 (formerly 1D12) 图 4 — Image 4 / 6Western blot analysis of extracts (10ug) from a mouse cell line and 3 different mouse tissues by using anti-BIRC7 monoclonal antibody (1:200).

Anti-BIRC7 (Livin) mouse monoclonal antibody, clone OTI1D12 (formerly 1D12) 图 5 — Image 5 / 6Immunohistochemical staining of paraffin-embedded Carcinoma of liver tissue using anti-BIRC7mouse monoclonal antibody. Heat-induced epitope retrieval by EDTA solution buffer pH 8.0 at 120°C for 3 min.

Anti-BIRC7 (Livin) mouse monoclonal antibody, clone OTI1D12 (formerly 1D12) 图 6 — Image 6 / 6Flow cytometric analysis of Jurkat cells, using anti-BIRC7 antibody (GAM611869), (Red) compared to a nonspecific negative control antibody (Blue).

Product Specifications

SpecificationsProduct Specifications

Core Attributes CORE ATTRIBUTES

Species Reactivity: Human

Applications: FCIHCWB

Clone name: OTI1D12

Calculated molecular weight: 32.8 kDa

Immunogen: Full length human recombinant protein of human BIRC7 (NP_071444) produced in HEK293T cell.

Isotype: IgG1

Host species: Mouse

Clonality: Monoclonal

Purification method: Affinity Purification

Uniprot-A: Q96CA5

Recommended Dilution RECOMMENDED DILUTION

WB: 1:1000

IHC: 1:50

Product Properties PRODUCT PROPERTIES

Shipping: They are shipped out with dry ice/blue ice unless customers require otherwise

Storage Condition: Store at -20°C PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.Stable for 12 months from date of receipt.

Formulation: Liquid

Storage Buffer: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

The protein encoded by this gene is a member of the family of inhibitor of apoptosis proteins (IAP) and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Two transcript variants encoding different isoforms have been found for this gene. The two isoforms have different antiapoptotic properties, with isoform alpha protecting cells from apoptosis induced by staurosporine and isoform b protecting cells from apoptosis induced by etoposide.