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Mouse Monoclonal AntibodiesCat. No. GAM615455

COPS5 (JAB1) mouse monoclonal antibody, clone OTI2B12 (formerly 2B12)

Name: COPS5 (JAB1) mouse monoclonal antibody, clone OTI2B12 (formerly 2B12)
SKU: GAM615455
Price: 169 CNY
Availability: InStock

AliasesCOPS5

ReactivityHuman / Mouse / Rat

ApplicationsIF · IHC · WB

Host / ClonalityMouse / Monoclonal

Lead timeIn stock · ships in 48h

$169/ 50μlIn stock 200 · Ready to ship

50μl$169

100μl$299

Applications & Recommended Dilution

Applications & DilutionRecommended Dilution

Recommended dilutionNo data

Reactivity: Human / Mouse / Rat
Assay: IF

IHC

Recommended dilution1:150

Reactivity: Human / Mouse / Rat
Assay: IHC

Recommended dilution1:2000

Reactivity: Human / Mouse / Rat
Assay: WB

Product Images

Product ImagesImages

COPS5 (JAB1) mouse monoclonal antibody, clone OTI2B12 (formerly 2B12) 图 1 — Image 1 / 15Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-COPS5 mouse monoclonal antibody. Heat-induced epitope retrieval by EDTA solution buffer pH 8.0 at 120°C for 3 min.

COPS5 (JAB1) mouse monoclonal antibody, clone OTI2B12 (formerly 2B12) 图 2 — Image 2 / 15Immunohistochemical staining of paraffin-embedded Carcinoma of Human kidney tissue using anti-COPS5 mouse monoclonal antibody. Heat-induced epitope retrieval by EDTA solution buffer pH 8.0 at 120°C for 3 min.

COPS5 (JAB1) mouse monoclonal antibody, clone OTI2B12 (formerly 2B12) 图 3 — Image 3 / 15Immunohistochemical staining of paraffin-embedded Carcinoma of Human liver tissue using anti-COPS5 mouse monoclonal antibody. Heat-induced epitope retrieval by EDTA solution buffer pH 8.0 at 120°C for 3 min.

COPS5 (JAB1) mouse monoclonal antibody, clone OTI2B12 (formerly 2B12) 图 4 — Image 4 / 15Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-COPS5 mouse monoclonal antibody. Heat-induced epitope retrieval by EDTA solution buffer pH 8.0 at 120°C for 3 min.

COPS5 (JAB1) mouse monoclonal antibody, clone OTI2B12 (formerly 2B12) 图 5 — Image 5 / 15Immunohistochemical staining of paraffin-embedded Human Ovary tissue within the normal limits using anti-COPS5 mouse monoclonal antibody. Heat-induced epitope retrieval by EDTA solution buffer pH 8.0 at 120°C for 3 min.

COPS5 (JAB1) mouse monoclonal antibody, clone OTI2B12 (formerly 2B12) 图 6 — Image 6 / 15Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-COPS5 mouse monoclonal antibody. Heat-induced epitope retrieval by EDTA solution buffer pH 8.0 at 120°C for 3 min.

COPS5 (JAB1) mouse monoclonal antibody, clone OTI2B12 (formerly 2B12) 图 7 — Image 7 / 15Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-COPS5 mouse monoclonal antibody. Heat-induced epitope retrieval by EDTA solution buffer pH 8.0 at 120°C for 3 min.

COPS5 (JAB1) mouse monoclonal antibody, clone OTI2B12 (formerly 2B12) 图 8 — Image 8 / 15Immunohistochemical staining of paraffin-embedded Carcinoma of Human pancreas tissue using anti-COPS5 mouse monoclonal antibody. Heat-induced epitope retrieval by EDTA solution buffer pH 8.0 at 120°C for 3 min.

COPS5 (JAB1) mouse monoclonal antibody, clone OTI2B12 (formerly 2B12) 图 9 — Image 9 / 15Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-COPS5 mouse monoclonal antibody. Heat-induced epitope retrieval by EDTA solution buffer pH 8.0 at 120°C for 3 min.

COPS5 (JAB1) mouse monoclonal antibody, clone OTI2B12 (formerly 2B12) 图 10 — Image 10 / 15Immunohistochemical staining of paraffin-embedded Human prostate tissue within the normal limits using anti-COPS5 mouse monoclonal antibody. Heat-induced epitope retrieval by EDTA solution buffer pH 8.0 at 120°C for 3 min.

COPS5 (JAB1) mouse monoclonal antibody, clone OTI2B12 (formerly 2B12) 图 11 — Image 11 / 15Immunohistochemical staining of paraffin-embedded Carcinoma of Human prostate tissue using anti-COPS5 mouse monoclonal antibody. Heat-induced epitope retrieval by EDTA solution buffer pH 8.0 at 120°C for 3 min.

COPS5 (JAB1) mouse monoclonal antibody, clone OTI2B12 (formerly 2B12) 图 12 — Image 12 / 15Immunohistochemical staining of paraffin-embedded Human bladder tissue within the normal limits using anti-COPS5 mouse monoclonal antibody. Heat-induced epitope retrieval by EDTA solution buffer pH 8.0 at 120°C for 3 min.

COPS5 (JAB1) mouse monoclonal antibody, clone OTI2B12 (formerly 2B12) 图 13 — Image 13 / 15Immunohistochemical staining of paraffin-embedded Carcinoma of Human bladder tissue using anti-COPS5 mouse monoclonal antibody. Heat-induced epitope retrieval by EDTA solution buffer pH 8.0 at 120°C for 3 min.

COPS5 (JAB1) mouse monoclonal antibody, clone OTI2B12 (formerly 2B12) 图 14 — Image 14 / 15Immunohistochemical staining of paraffin-embedded Human tonsil within the normal limits using anti-COPS5 mouse monoclonal antibody. Heat-induced epitope retrieval by EDTA solution buffer pH 8.0 at 120°C for 3 min.

COPS5 (JAB1) mouse monoclonal antibody, clone OTI2B12 (formerly 2B12) 图 15 — Image 15 / 15Anti-COPS5 mouse monoclonal antibody (GAM615455) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY COPS5

Product Specifications

SpecificationsProduct Specifications

Core Attributes CORE ATTRIBUTES

Species Reactivity: HumanMouseRat

Applications: IFIHCWB

Clone name: OTI2B12

Calculated molecular weight: 37.4 kDa

Immunogen: Full length human recombinant protein of human COPS5(NP_006828) produced in HEK293T cell.

Isotype: IgG1

Host species: Mouse

Clonality: Monoclonal

Purification method: Affinity Purification

Uniprot-A: Q92905

Recommended Dilution RECOMMENDED DILUTION

WB: 1:2000

IHC: 1:150

Product Properties PRODUCT PROPERTIES

Shipping: They are shipped out with dry ice/blue ice unless customers require otherwise

Storage Condition: Store at -20°C PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.Stable for 12 months from date of receipt.

Formulation: Liquid

Storage Buffer: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors. [provided by RefSeq]