FCGR3A mouse monoclonal antibody, clone OTI12H8

Name: FCGR3A mouse monoclonal antibody, clone OTI12H8
SKU: GAM924746
Price: 960 CNY
Availability: InStock

检索别名FCGR3A

反应种属Human

应用FC

来源 / 克隆性Mouse / Monoclonal

货期现货 · 48h 发货

¥960/ 50μl库存 199 · 现货

50μl¥960

100μl¥1660

应用与推荐稀释比

Applications & DilutionRecommended Dilution

推荐稀释比暂无数据

反应种属: Human
检测平台: FC

产品图集

Product ImagesImages

FCGR3A mouse monoclonal antibody, clone OTI12H8 图 1 — 图 1Flow cytometric analysis of living 293T cells transfected with FCGR3A overexpression plasmid, Red)/empty vector (Blue) using anti-FCGR3A antibody (GAM924746). Cells incubated with a non-specific antibody (Green) were used as isotype control.（1:100）

产品参数

SpecificationsProduct Specifications

核心指标 CORE ATTRIBUTES

反应种属: Human

应用: FC

克隆号: OTI12H8

预测分子量: 29.09 kDa

免疫源: Full length human recombinant protein of human FCGR3A (NP_001121065) produced in HEK293T cell.

Isotype: IgG2b

来源: Mouse

克隆性: Monoclonal

纯化方式: Affinity Purification

Uniprot-A: P08637

产品特性 PRODUCT PROPERTIES

运输条件: They are shipped out with dry ice/blue ice unless customers require otherwise

储存条件: Store at -20°C PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.Stable for 12 months from date of receipt.

产品形态: Liquid

储存缓冲液: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].